Originally Posted by
WLIU
It sounds like you need to start with a textbook on what mechanical engineers call "statics". R.C. Hibbeler is the text most commonly used in university classrooms. Covers calculating the strength of different shaped elements like tubes and I beams. Then 14 CFR Part 23 and the advisory circular that expands on those strength performance requirements will give you the input loads you need to design for.
You can also purchase plans for an existing homebuilt aircraft similar to what you want to build and look at how that aircraft design uses fuselage trusses.
Best of luck,
Wes